Zaldiar 37,5mg – Possible Side Effects
As with any medication, ZALDIAR may cause some unwanted effects. If you are worried about the side effects, talk to your doctor. The most serious adverse effects reported are: hypertension, tachycardia, arrhythmia, convulsion, dyspnoea and bleeding in the intestine (melaena). The most commonly reported adverse effects are:
* nausea
* dizziness
* somnolence
These effects were observed in more than 10% of the patients treated with ZALDIAR. Most were usually mild and not troublesome. 1 – 10% of patients may experience:
Vomiting, constipation, flatulence, diarrhoea, stomach pain, digestion problems, a dry mouth, headache, agitation, confusion, sleep disorders, mood changes, anxiety, nervousness, euphoria (a sense of feeling ‘high’ all the time), increased sweating, itching. 0,1 – 1% of patients may develop:
Heart rhythm and heart rate disorders, changes in blood pressure, difficulty or pain on passing urine/ protein in the urine, skin reactions/ urticaria, ringing in the ear, depression, nightmares, hallucinations (hearing, seeing or sensing things that are not really there), loss of memory, difficulty swallowing, blood in the stools, shivers, hot flushes, pains in the chest, uncoordinated movement, muscle cramps, unusual tingling feeling, convulsions, drug dependence, blurred vision, shortness of breath, raised liver enzymes. Do not be alarmed by the above lists – you may not experience any of these effects. However, if you do notice any of these effects, or any other unusual symptoms, please tell your doctor or pharmacist as soon as possible. The following are recognized side effects, which have been reported by people using medications that contain only tramadol or only paracetamol. However, if you experience any of these while taking ZALDIAR, you should tell your doctor:
Tramadol:
* Feeling faint when getting up from a lying or sitting position
* Slow heart rate
* Fainting
* Mood changes, changes in activity
* Allergic reactions, such as itching, swollen face or lips, or shortness of breath,
* Changes in appetite, weakness, difficulty breathing,
* Agitation, anxiety, nervousness, sleep disorders, hyperactivity, tremors and gastrointestinal symptoms.
* Worsening of existing asthma.
Paracetamol:
* Allergic reactions with rash
* Thrombocytopenia, where the number of platelets in the blood is reduced or agranulocytosis which is characterized by the decrease or absence of leukocytes
* A deficiency of prothrombin in the blood
If you notice any other reaction not mentioned in this leaflet, consult your doctor or pharmacist.



