Pill Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Symptoms of too much medicine being absorbed into the bodyVery rare
Dizziness or drowsiness
increased sweating
irregular heartbeat
muscle twitching or trembling
nausea or vomiting
shortness of breath or troubled breathing
unusual excitement, nervousness, or restlessness
unusual tiredness or weakness

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Rare
Fever
skin rash or itching
sore throat
unusual tiredness and weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
Abdominal pain
diarrhea
dizziness
headache
nausea
vomiting
Rare
Thinning or loss of hair
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare
Blood-containing blisters on skin
burning and itching of skin
increased skin sensitivity
lack of healing of skin condition
numbness in fingers
painful, red or itchy, pus-containing blisters in hair follicles
raised, dark red, wart-like spots on skin, especially when used on the face
skin infection
thinning of skin with easy bruising
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare – usually mild and transient
Burning, dryness, irritation, itching, or redness of skin
increased redness or scaling of skin sores
skin rash
When the gel, lotion, solution, or aerosol form of this medicine is applied, a mild, temporary stinging may be expected.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Agitation; blurred vision; constipation; dizziness or lightheadedness when sitting up or standing; drowsiness; dry mouth, nose, or throat; nausea; nervousness; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); anxiety; behavior changes; chest pain; confusion; disorientation; exaggerated sense of well-being; fast, slow, or irregular heartbeat; flushing; hallucinations; loss of coordination; memory loss; mood or mental changes; seizures; trouble urinating.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

With overuse or long-term use
Increase in eye irritation
Symptoms of too much medicine being absorbed into the body
Dizziness
headache
increased sweating
nausea
nervousness
weakness
Symptoms of overdose
Decrease in body temperature
drowsiness
slow heartbeat
weakness (severe)
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare
Blurred vision
large pupils
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
Dizziness, severe
feeling of choking, irritation, or swelling in throat
flushing or redness of skin
increased shortness of breath
skin rash
swelling of face, lips, or eyelids
tightness in chest or wheezing, troubled breathing
Incidence not known (for salmeterol)
Difficulty breathing
noisy breathing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
Fast heartbeat
headache
nervousness
trembling
Less common
Coughing or other bronchial irritation
dizziness or light-headedness
dryness or irritation of mouth or throat
Rare
Chest discomfort or pain
drowsiness or weakness
irregular heartbeat
irritation of throat or mouth
muscle cramps or twitching
nausea and/or vomiting
restlessness
trouble in sleeping
Not all of the side effects listed above have been reported for each of these medicines, but they have been reported for at least one of them. All of the adrenergic bronchodilators are similar, so any of the above side effects may occur with any of these medicines.

While you are using an adrenergic bronchodilator, you may notice an unusual or unpleasant taste. This may be expected and will go away when you stop using the medicine.

Isoproterenol may cause the saliva to turn pinkish to red. This is to be expected while you are taking this medicine.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common or rare
Less common or rare with azatadine, cetirizine, clemastine, cyproheptadine, desloratadine, dexchlorpheniramine, diphenhydramine, or loratadine

Abdominal or stomach pain
burning
chills
clay-colored stools or dark urine
cough
diarrhea
difficulty swallowing
dizziness
fast or irregular heartbeat
fever
headache
hives
itching
prickly sensations
puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
redness of skin
seizures
shortness of breath
skin rash
swelling
tightness in chest
tingling
unusual tiredness or weakness
wheezing
Check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare
Sore throat
unusual bleeding or bruising
unusual tiredness or weakness
Symptoms of overdose
Clumsiness or unsteadiness
convulsions (seizures)
drowsiness (severe)
dryness of mouth, nose, or throat (severe)
feeling faint
flushing or redness of face
hallucinations (seeing, hearing, or feeling things that are not there)
shortness of breath or troubled breathing
trouble in sleeping
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
Drowsiness
dry mouth, nose, or throat
gastrointestinal upset, stomach pain, or nausea
headache
increased appetite and weight gain
thickening of mucus
Less common or rare
Acid or sour stomach
belching
blurred vision or any change in vision
body aches or pain
clumsiness or unsteadiness
confusion (not with diphenhydramine)
congestion
constipation
cough
diarrhea
difficult or painful urination
difficulty in moving
difficult or painful menstruation
dizziness (not with brompheniramine or hydroxyzine)
drowsiness (with high doses of desloratadine and loratadine)
dryness of mouth, nose, or throat
early menstruation
fast heartbeat
fever
heartburn
hoarseness
increased sensitivity of skin to sun
increased sweating
indigestion
loss of appetite
joint pain
muscle aching or cramping
muscle pains or stiffness
nausea
nightmares (not with azatadine, chlorpheniramine, cyproheptadine, desloratadine, hydroxyzine, or loratadine)
ringing or buzzing in ears
runny nose
skin rash
swollen joints
stomach discomfort, upset or pain
tender swollen glands in neck
tremor
unusual excitement, nervousness, restlessness, or irritability
vomiting

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Symptoms of too much medicine being absorbed into the body

Blurred vision
fast, irregular, or pounding heartbeat
headache, dizziness, drowsiness, or lightheadedness
high blood pressure
nervousness
trembling
trouble in sleeping
weakness.
Increase in runny or stuffy nose
The above side effects are more likely to occur in children because there is a greater chance in children that too much of this medicine may be absorbed into the body.

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Burning, dryness, or stinging inside of nose
increase in nasal discharge
sneezing

The incidence of adverse events during treatment with nifedipine extended-release tablets in doses up to 90 mg daily were derived from multi-center placebo-controlled clinical trials in 370 hypertensive patients. Atenolol 50 mg once daily was used concomitantly in 187 of the 370 patients on nifedipine extended-release tablets and in 64 of the 126 patients on placebo. All adverse events reported during nifedipine extended-release tablets therapy were tabulated independently of their causal relationship to medication.

The most common adverse event reported with nifedipine extended-release tablets was peripheral edema. This was dose related and the frequency was 18% on nifedipine extended-release tablets 30 mg daily, 22% on nifedipine extended-release tablets 60 mg daily and 29% on nifedipine extended-release tablets 90 mg daily versus 10% on placebo.

Other common adverse events reported in the above placebo-controlled trials include:

NIFEDIPINE EXTENDED-
RELEASE TABLETS (%) PLACEBO (%)
(n=370) (n=126)
Adverse Event
Headache 19 13
Flushing/heat sensation 4 0
Dizziness 4 2
Fatigue/asthenia 4 4
Nausea 2 1
Constipation 1 0

Where the frequency of adverse events with nifedipine extended-release tablets and placebo is similar, causal relationship cannot be established.

The following adverse events were reported with an incidence of 3% or less in daily doses up to 90 mg:

Body as a Whole/Systemic: chest pain, leg pain

Central Nervous System: paresthesia, vertigo

Dermatologic: rash

Gastrointestinal: constipation

Musculoskeletal: leg cramps

Respiratory: epistaxis, rhinitis

Urogenital: impotence, urinary frequency

Other adverse events reported with an incidence of less than 1.0% were:

Body as a Whole/Systemic: allergic reaction, asthenia, cellulitis, substernal chest pain, chills, facial edema, lab test abnormal, malaise, neck pain, pelvic pain, pain, photosensitivity reaction

Cardiovascular: atrial fibrillation, bradycardia, cardiac arrest, extrasystole, hypotension, migraine, palpitations, phlebitis, postural hypotension, tachycardia, cutaneous angiectases

Central Nervous System: anxiety, confusion, decreased libido, depression, hypertonia, hypesthesia, insomnia, somnolence

Dermatologic: angioedema, petechial rash, pruritus, sweating

Gastrointestinal: abdominal pain, diarrhea, dry mouth, dysphagia, dyspepsia, eructation, esophagitis, flatulence, gastrointestinal disorder, gastrointestinal hemorrhage, GGT increased, gum disorder, gum hemorrhage, vomiting

Hematologic: eosinophilia, lymphadenopathy

Metabolic: gout, weight loss

Musculoskeletal: arthralgia, arthritis, joint disorder, myalgia, myasthenia

Respiratory: dyspnea, increased cough, rales, pharyngitis, stridor

Special Senses: abnormal vision, amblyopia, conjunctivitis, diplopia, eye disorder, eye hemorrhage, tinnitus

Urogenital/Reproductive: dysuria, kidney calculus, nocturia, breast engorgement, polyuria, urogenital disorder

The following adverse events have been reported rarely in patients given nifedipine in coat core or other formulations: allergenic hepatitis, alopecia, anaphylactic reaction, anemia, arthritis with ANA (+), depression, erythromelalgia, exfoliative dermatitis, fever, gingival hyperplasia, gynecomastia, hyperglycemia, jaundice, leukopenia, mood changes, muscle cramps, nervousness, paranoid syndrome, purpura, shakiness, sleep disturbances, Stevens-Johnson syndrome, syncope, taste perversion, thrombocytopenia, toxic epidermal necrolysis, transient blindness at the peak of plasma level, tremor and urticaria.