Pill Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common
Blisters on skin
body aches or pain
chills
cough
difficulty in breathing
ear congestion
itching in genital or other skin areas
loss of voice
nasal congestion
open sores or scabs on skin
pain or tenderness around eyes and cheekbones
redness of skin (severe)
scaling
shortness of breath or troubled breathing
skin rash
sneezing
sore throat
stuffy or runny nose
tightness of chest or wheezing
unusual tiredness or weakness
Less common
Abdominal pain
ankle, knee, or great toe joint pain
blurred vision
chest pain
dizziness
bladder pain
bloody or cloudy urine
cold flu-like symptoms
difficult, burning, or painful urination
fainting
fast or irregular heartbeat
frequent urge to urinate
joint stiffness or swelling
high amount of cholesterol in the blood
hoarseness
lower back or side pain
lump in abdomen
nervousness
persistent non-healing sore
pink growth on skin
pounding in the ears
reddish patch or irritated area
severe headache
shiny bump on skin
slow or fast heartbeat
swollen, painful, or tender lymph glands in neck, armpit, or groin
white, yellow or waxy scar-like area
Incidence unknown – Observed during clinical practice, estimates of frequency can not be determined
Blurred vision
blue lips and fingernails
convulsions
coughing that sometimes produces a pink frothy sputum
difficulty breathing
dilated neck veins
dizziness
extreme fatigue
faintness
fast, irregular or pounding heartbeat
headache
irregular breathing
irregular heartbeat
nausea or vomiting
pain in the shoulders, arms, jaw or neck
seizures
shortness of breath
slurred speech
sudden and severe inability to speak
suicide
sweating
swelling of face, fingers, feet, or lower legs
temporary blindness
weakness in arm and/or leg on one side of the body
weight gain
wheezing
Symptoms of overdose
Flu-like symptoms, including diarrhea, fatigue, fever, headache, or muscle pain
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
Burning or stinging of skin (mild)
flaking of skin
mild headache
pain, soreness, or tenderness of skin (mild)
rash
redness of skin (mild)
swelling at place of application
Less common
Back pain
fever
lightening of the treated skin
nausea

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known
Abdominal or stomach cramping, burning, or tenderness
back or leg pains
bleeding gums
blistering, peeling, loosening of skin
bloating
bloody or black, tarry stools
bloody or cloudy urine
blue lips and fingernails
blurred vision
burning, crawling, itching, numbness, prickling, “pins and needles” , or tingling feelings
chest pain
chills
clay-colored stools
clear or bloody discharge from nipple
cloudy urine
confusion
constipation
cough or hoarseness
coughing that sometimes produces a pink frothy sputum
coughing up blood
dark urine
decrease in urine-concentrating ability
decreased appetite
diarrhea
difficult, fast, noisy breathing, sometimes with wheezing
difficulty swallowing
dimpling of breast skin
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
dry mouth
fast or irregular heartbeat
fever with or without chills
flushed, dry skin
fruit-like breath odor
general body swelling
general feeling of discomfort or illness
greatly decreased frequency of urination or amount of urine
headache
heartburn
hives or welts
increased blood pressure
increased hunger
increased thirst
increased urination
increased sweating
indigestion
inverted nipple
joint pain, stiffness, or swelling
loss of appetite
lower back or side pain
lump in breast or under the arm
muscle cramps or pain
nausea and vomiting
nosebleeds
numbness, tingling, pain, or weakness in hands, feet, or lips
painful or difficult urination
pains in stomach, side, or abdomen, possibly radiating to the back
pale skin
persistent crusting or scaling of nipple
pinpoint red or purple spots on skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
red, irritated eyes
redness or swelling of breast
redness, soreness or itching skin
seizures
severe stomach pain
shakiness and unsteady walk
shortness of breath
skin rash
sore on the skin of the breast that does not heal
sore throat
sores, ulcers, or white spots on lips or in mouth
sugar in the urine
swelling in legs and ankles
swelling of face, hands, fingers, feet, or lower legs
swollen or painful glands
thickening of bronchial secretions
tightness in chest
trembling
troubled breathing
unpleasant breath odor
unsteadiness, trembling, or other problems with muscle control or coordination
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight loss
vomiting of blood or material that looks like coffee grounds
weakness and heaviness of legs
weight gain
wheezing
yellow eyes or skin
Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose
Difficulty sleeping
disorientation
drowsiness to profound coma
hallucination
lethargy
lightheadedness
mood or other mental changes
rash with flat lesions or small raised lesions on the skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
Absent, missed, or irregular menstrual periods
bleeding after menopause
burning feeling in chest or stomach
discoloration of skin
feeling of constant movement of self or surroundings
inability to have or keep an erection
increased sensitivity of skin to sunlight
muscle spasm
restlessness
sensation of spinning
severe sunburn
stomach upset
stopping of menstrual bleeding
swelling of the breasts or breast soreness in both females and males

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cough; diarrhea; dry skin, pain, swelling, or soreness of the mouth or tongue; fingernail or toenail changes; headache; itching; loss of appetite; nausea; nosebleed; stomach pain or upset; taste changes; trouble sleeping; vomiting; tiredness or weakness; weight loss.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; flushing, tightness in the chest; swelling of the mouth, face, lips, or tongue, unusual hoarseness); arm or leg pain; bloody stools; chest pain; decreased, difficult, or painful urination; dry mouth or increased thirst; fast or irregular heartbeat; fever, chills, or persistent sore throat; new or worsening cough; numbness or tingling; severe or persistent diarrhea, nausea, stomach pain, or vomiting; severe or persistent dizziness or headache; severe or persistent tiredness or weakness; shortness of breath, or other breathing problems; swelling of the arms, hands, feet, or ankles; symptoms of high blood sugar (eg, increased hunger, thirst, or urination; confusion; unusual drowsiness); unusual bruising or bleeding; yellowing of the eyes or skin.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:
fast, pounding, or uneven heartbeat;

nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or

easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms.

Less serious side effects may include:

dry eyes, nose, and mouth;

drowsiness or dizziness;

blurred vision;

urinating less than usual; or

feeling restless or excited (especially in children).

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking ACTOplus met.

Side effects may include:
Diarrhea, dizziness, headache, nausea, sinusitis, upper respiratory tract infection, upset stomach, urinary tract infection, water retention, weight gain
Symptoms of lactic acidosis (if these occur, call your doctor immediately):
Dizziness or light-headedness; feeling very weak, tired, or uncomfortable; low body temperature; muscle pain; rapid breathing that you can’t explain; slow or uneven heartbeat; stomach problems (such as nausea or vomiting); unusual sleepiness
Symptoms of liver problems (if these occur, call your doctor immediately):
Dark urine, loss of appetite, nausea or vomiting, stomach pain, tiredness, yellowing of your skin or whites of your eyes

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare
Yellow eyes or skin
Symptoms of overdose
Diarrhea
increased sweating
loss of appetite
nausea or vomiting
stomach cramps or pain
swelling, pain, or tenderness in the upper abdomen or stomach area
Check with your doctor as soon as possible if any of the following side effects occur:

Rare
Bloody or black, tarry stools
bloody or cloudy urine
fever with or without chills (not present before treatment and not caused by the condition being treated)
pain in lower back and/or side (severe and/or sharp)
pinpoint red spots on skin
skin rash, hives, or itching
sores, ulcers, or white spots on lips or in mouth
sore throat (not present before treatment and not caused by the condition being treated)
sudden decrease in amount of urine
unusual bleeding or bruising
unusual tiredness or weakness

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability (especially in children); headache; loss of appetite; nausea; nervousness; restlessness; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; chest pain; decreased coordination; difficulty urinating; fast or irregular heartbeat; fever; hallucinations; seizure; severe dizziness and drowsiness; severe nervousness, anxiety, or restlessness; tremors; unusual weakness.

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); loss of appetite; muscle weakness; nausea; slow reflexes; vomiting.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:
chest pain, fast or pounding heartbeats;

pale or yellowed skin, dark colored urine, fever, confusion or weakness;

mood changes, confusion, anxiety;

tremors or shaking;

easy bruising or bleeding;

sore throat, body aches, flu symptoms; or

pain or swelling in one or both legs.

Less serious side effects may include:

mild nausea, vomiting, upset stomach;

loss of appetite;

headache; or

hair loss.

Adverse reactions, occurring most often early in therapy, include paresthesias, particularly a “tingling” feeling in the extremities, hearing dysfunction or tinnitus, loss of appetite, taste alteration and gastrointestinal disturbances such as nausea, vomiting and diarrhea; polyuria, and occasional instances of drowsiness and confusion.

Metabolic acidosis and electrolyte imbalance may occur.

Transient myopia has been reported. This condition invariably subsides upon diminution or discontinuance of the medication.

Other occasional adverse reactions include urticaria, melena, hematuria, glycosuria, hepatic insufficiency, flaccid paralysis, photosensitivity and convulsions.